Unzip pulse.zip and upload the all the files/folders inside to the root of your domain. Do not upload the "pulse" folder itself, just the files/folders inside of it. However, if you wish to install into a sub-folder for development, then you can upload the whole package as domain.com/pulse.
Edit config.php to set your options/password. If you did install into a sub-folder, you will need to change the path setting here. This path change is also needed if, for example, installing locally with MAMP.
For more: How to install Pulse CMS